Bumetanide

Overview

Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na + -K + -Cl + cotransporter ( NKCC ) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC 50 s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively.

Application

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Product Information

• Catalog No.: HY-17468
• CAS No.: 28395-03-1
• Molecular Formula: C17H20N2O5S
• Molecular Weight: 364.42
• Purity: 99.90%
• Storage: 4°C, protect from light * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.86 mM); Clear solution
• Availability: In-stock

Source

Original product source