Y040-7904

Overview

Y040-7904 is a mitophagy activator . Y040-7904 enhances mitophagy by promoting mitochondria transport to autophagosomes and the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitophagy through the SIRT1/FoxO3 pathway. Y040-7904 upregulates the levels of Parkin, PINK1, and LC3II/I. Y040-7904 reduces amyloid-β ( Aβ ) accumulation in both in vitro and in vivo models of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Mitophagy | Products > Signaling Pathways > PINK1/Parkin | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-174806
• CAS No.: 889662-19-5
• Molecular Formula: C20H18O7
• Molecular Weight: 370.35
• Purity: 99.36%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 5 mg/mL (13.50 mM); Clear solution
• Availability: In-stock

Source

Original product source