MAO-B-IN-44 (Compound 4n) is a selective monoamine oxidase B ( MAO-B ) inhibitor targetin with an IC 50 value of 1.01 μM, showing weak inhibition on MAO-A ( IC 50 =14.4 μM). MAO-B-IN-44 reduces degradation of neurotransmitters like dopamine. MAO-B-IN-44 is promising for research of neurodegenerative diseases related to MAO-B abnormalities such as Parkinson’s disease.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Oxidase
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