HTS05585

Overview

HTS05585 (Compound Hit-1) is a selective macrophage migration inhibitory factor ( MIF ) inhibitor with a K d value of 0.29 μM measured by microscale thermophoresis (MST) and 0.32±0.01 μM verified by isothermal titration calorimetry (ITC). HTS05585 inhibits the release of pro-inflammatory factors (TNF-α, IL-6 , IL-1β) from LPS-induced macrophages. HTS05585 is promising for research of inflammation-related diseases such as sepsis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Macrophage migration inhibitory factor (MIF)

Product Information

• Catalog No.: HY-174842
• CAS No.: 696643-14-8
• Molecular Formula: C18H15N3O
• Molecular Weight: 289.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source