ALG-097558

Overview

ALG-097558 is an orally active 3CLpro inhibitor. ALG-097558 demonstrates pan-coronavirus activity against various SARS-CoV-2 variants as well as other human coronaviruses (HCoVs) such as SARS-CoV-1 , α-HCoV 229E, and β-HCoV OC43. ALG-097558 demonstrates potent inhibition with IC 50 s of 2 nM (SARS-CoV-2 3CLpro) and 6 nM (229E 3CLpro). ALG-097558 demonstrates antiviral activity in the SARS-CoV-2 hamster infection model. ALG-097558 can be used for the study of viral infections[1].

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > 3-Chymotrypsin-Like Protease | Products > Disease Areas > MERS-CoV Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-175029
• CAS No.: 2892287-29-3
• Molecular Formula: C25H32ClF2N5O4
• Molecular Weight: 540.00
• Purity: 98.18%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution
• Availability: In-stock

Source

Original product source