Rosuvastatin-d 3

Overview

Rosuvastatin-d 3 (ZD 4522-d 3 ) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC 50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC 50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR) | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-17504AS
• CAS No.: 1133429-16-9
• Molecular Formula: C22H25D3FN3O6S
• Molecular Weight: 484.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source