Rosuvastatin Sodium

Overview

Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC 50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC 50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 ( Hsp70 ) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol , triglycerides, and C-reactive protein levels.

Application

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Product Information

• Catalog No.: HY-17504B
• CAS No.: 147098-18-8
• Molecular Formula: C22H27FN3NaO6S
• Molecular Weight: 503.52
• Purity: 99.91%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.08 mg/mL (4.13 mM); Clear solution
• Availability: In-stock

Source

Original product source