MT-228

Overview

MT-228 (BPN-0026709) is a selective and blood-brain barrier permeable non-muscle myosin II inhibitor. MT-228 markedly improves tolerability by selectively targeting NMIIB ( K I = 1.5 μM) over CMII ( K I = 17 μM), and the sequence of SmMll MD is 83.6% identical to that of NMllB. MT-228 shows long-lasting efficacy in animal models of stimulant use disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Myosin

Product Information

• Catalog No.: HY-175199
• CAS No.: 2404652-24-8
• Molecular Formula: C19H19N3O3
• Molecular Weight: 337.37
• Purity: 99.9%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 0.83 mg/mL (2.46 mM); Clear solution
• Availability: In-stock

Source

Original product source