DHC-286

Overview

DHC-286 is a molecular glue degrader targeting GSPT1 . DHC-286 recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, promoting GSPT1 ubiquitination and proteasomal degradation, inducing cytotoxicity. DHC-286 is promising for research of cancers such as acute myeloid leukemia.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Molecular Glues

Product Information

• Catalog No.: HY-175334
• CAS No.: 2920443-08-7
• Molecular Formula: C23H20F3N3O5
• Molecular Weight: 475.42
• Purity: 98.00%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source