NRA-0160 is a selective dopamine D4 receptor antagonist, with a K i value of 0.48 nM and with negligible affinity for dopamine D2 receptor ( K i : >10000 nM), D3 receptor ( K i : 39 nM), rat 5-HT2A receptor ( K i : 180 nM) and rat α1 adrenoceptor ( K i : 237 nM).
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