M6766

Overview

M6766 is a selective endoplasmic reticulum oxidoreductase 1α ( ERO1α ) inhibitor with an IC 50 of 1.4 μM and a K D of 1.1 μM. M6766 also inhibits ERO1β with an IC 50 of 7.2 μM. M6766 binds to the flavin adenine dinucleotide-binding pocket in ERO1α. M6766 inhibits granule secretion, αIIbβ3 integrin activation, Ca 2+ mobilization, and platelet aggregation. M6766 can be used for the research of neurological disease , such as ischemic stroke.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endoplasmic Reticulum Oxidoreductase 1 (ERO1) | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-175593
• CAS No.: 696628-90-7
• Molecular Formula: C19H16N6S
• Molecular Weight: 360.44
• Purity: 99.43%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source