NGI-235

Overview

NGI-235 is an STT3A -selective oligosaccharyltransferase complex OST-A inhibitor. NGI-235 preferentially inhibits OST-A catalytic activity, impairing N-glycosylation of OST-A substrates. NGI-235 causes the hypoglycosylation of both TLR4 , GLUT1 and inhibits NF-κB signaling. NGI-235 can be used for the research of inflammation.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > GLUT

Product Information

• Catalog No.: HY-175674
• CAS No.: 2763063-40-5
• Molecular Formula: C25H30N4O3S2
• Molecular Weight: 498.66
• Purity: 99.70%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source