P2Y1 antagonist 4

Overview

P2Y1 antagonist 4 is a selective P2Y1 receptor antagonist with excellent blood-brain barrier (BBB) penetration. P2Y1 antagonist 4 inhibits P2Y1 receptor -mediated cytosolic Ca 2+ increase ( IC 50 = 1.95 μM) and platelet aggregation ( IC 50 = 3.24 μM) induced by ADP in rabbit washed platelets. P2Y1 antagonist 4 significantly upregulates the level of nuclear Nrf2 protein in H2O2-treated HT22 cells. P2Y1 antagonist 4 reduces myocardial infarct size in a mouse acute myocardial infarction (MI) model. P2Y1 antagonist 4 can be used for the study of ischemic stroke and myocardial infarction.

Application

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Product Information

• Catalog No.: HY-175675
• CAS No.: 3104888-50-5
• Molecular Formula: C21H11F5N4O2
• Molecular Weight: 446.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source