CT-996

Overview

CT-996 is an orally active GLP-1RA agonist with an EC 50 of 0.49 nM. CT-996 reduces the recruitment of β-arrestin and the internalization of GLP-1R . CT-996 suppresses postprandial blood glucose in mice expressing human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkeys during intravenous glucose challenge. CT-996 can be used for the research of type 2 diabetes (T2D) and obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Arrestin | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-175701
• CAS No.: 2810808-95-6
• Molecular Formula: C30H31F2N5O5
• Molecular Weight: 579.59
• Purity: 99.97%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (4.31 mM); Clear solution
• Availability: In-stock

Source

Original product source