APL-1082

Overview

APL-1082 is a drug-Linker conjugate that can be used for ADC synthesis. APL-1082 contains Exatecan ( HY-13631 ) and Linker (HY-175929). APL-1082 reduces aggregation and hydrophobicity in Trastuzumab ( HY-P9907 ) ADCs, enables production of high-DAR (10) ADCs with homogeneity and defined physicochemical properties. APL-1082 forms a Trastuzumab ADC with enhanced stability, showing greater DAR retention over time. APL-1082 can be used for the research of gastric cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Drug-Linker Conjugates for ADC

Product Information

• Catalog No.: HY-175888
• CAS No.: 2921735-93-3
• Molecular Formula: C60H70FN11O16
• Molecular Weight: 1220.26
• Purity: 95.58%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source