Framycetin

Overview

Framycetin (Neomycin B), an aminoglycoside antibiotic , is a potent RNase P cleavage activity inhibitor with a K i of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a K i of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-17624
• CAS No.: 119-04-0
• Molecular Formula: C23H46N6O13
• Molecular Weight: 614.64
• Purity: 99.98%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source