Antitrypanosomal agent 26

Overview

Antitrypanosomal agent 26 (Compound 1) is an allosteric trypanosome alternative oxidase ( TAO ) inhibitor. Antitrypanosomal agent 26 exhibits potent activity against African animal trypanosomes (e.g., Trypanosoma brucei , etc.) with an IC 50 value of 1.3 nM for recombinant TAO. Antitrypanosomal agent 26 blocks the mitochondrial electron transport chain of trypanosomes and inhibits glucose-dependent respiration. Antitrypanosomal agent 26 is promising for research of African animal trypanosomiasis, such as bovine trypanosomiasis.

Application

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Product Information

• Catalog No.: HY-176253
• CAS No.: 2601665-22-7
• Molecular Formula: C39H49BrNO3P
• Molecular Weight: 690.69
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source