FASN/SCD-IN-1

Overview

FASN/SCD-IN-1 is a Silybin ( HY-N0779A ) derivative, an orally active inhibitor of Fatty Acid Synthase ( FASN )/ Stearoyl-CoA Desaturase ( SCD ). FASN/SCD-IN-1 has shown in vitro activity in inhibiting lipid deposition, reducing FASN and SCD transcriptional levels, and exhibiting antioxidant, anti-inflammatory, and anti-fibrotic activities. FASN/SCD-IN-1 has demonstrated significant hepatoprotective effects in a rat model of acute liver injury. FASN/SCD-IN-1 ameliorates the pathological features of MASH liver, including steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative steatohepatitis (MASH). FASN/SCD-IN-1 can be used to study MASH.

Application

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Product Information

• Catalog No.: HY-176274
• CAS No.: 3063509-61-2
• Molecular Formula: C25H22O9S
• Molecular Weight: 498.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source