(S)-CDK2 degrader 6

Overview

(S)-CDK2 degrader 6 (Compound 8) is the S-enantiomer of CDK2 degrader 6 ( HY-176444 ). (S)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC 50 of 166.7 nM in 24 h. (S)-CDK2 degrader 6 can be used for breast cancer research.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Molecular Glues

Product Information

• Catalog No.: HY-176444B
• CAS No.: 3083777-51-6
• Molecular Formula: C23H22F5N5O3
• Molecular Weight: 511.44
• Purity: 99.69%
• Storage: -20°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.89 mM); Clear solution
• Availability: In-stock

Source

Original product source