YM-58790 free base is a potent antagonist of mAChR . YM-58790 free base binds M1 , M2 , M3 with K i values of 28 nM, 260 nM, and 15 nM. YM-58790 free base exhibits potent inhibitory activity on bladder pressuer in reflexly-evoked rhythmic contraction in rats.
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