C3361 is a moderate specific Plasmodium falciparum hexose transporter 1 (PfHT1) and Plasmodium berghei hexose transporter 1 (PbHT1) inhibitor with K i values of 8.6 and 9.4 μM. C3361 inhibits TgGT1 with a K i of 82 μM. C3361 attenuates hepatic ( IC 50 = 15 μM) and ookinete development of P. berghei . C3361 can suppress the growth of blood-stage parasites . C3361 can be used for the research of infection , such as malaria.
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