JAK1-IN-18

Overview

JAK1-IN-18 (Example 2) is a selective JAK1 inhibitor with an IC 50 of 0.15 nM for JAK1 over JAK2 and JAK3 . JAK1-IN-18 significantly reduces inflammation in DSS ( HY-116282C )-induced ulcerative colitis (UC) mouse models and DNBS( HY-W324435 )-induced Crohn's disease (CD) rat models. JAK1-IN-18 can be used for autoimmune diseases (such as inflammatory bowel disease), viral infections (such as HBV infection) and cancers (such as blood cancer ) research.

Application

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Product Information

• Catalog No.: HY-176793
• CAS No.: 2459377-98-9
• Molecular Formula: C16H20F2N6O2
• Molecular Weight: 366.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source