Papaveroline

Overview

Papaveroline is a Fyn tyrosine kinase inhibitor, Na + ,K + -ATPase inhibitor with an I50 of 0.20 mM, Mg 2+ -ATPase inhibitor, K + -activated pNPPase inhibitor with an I50 of 1.51 mM, and apoptosis inducer. Papaveroline binds to the active site of Fyn tyrosine kinase and forms stable interactions with pocket amino acid residues. Papaveroline induces cell apoptosis , produces pycnotic and fragmented cell nuclei, and does not reduce intracellular ATP levels. Papaveroline is a dopamine-derived neurotoxin candidate associated with the pathogenesis of Parkinson's disease. Papaveroline can be used in the research of Alzheimer's disease and Parkinson's disease.

Application

Products | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Src | Products > Signaling Pathways > Na+/K+ ATPase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-176892
• CAS No.: 574-77-6
• Molecular Formula: C16H13NO4
• Molecular Weight: 283.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source