P38α-IN-10 (Compound 8) is an orally active inhibitor of p38α , with an IC₅₀ of 230 nM. P38α-IN-10 has an inhibitory effect on TNF production induced by LPS ( HY-D1056 ). P38α-IN-10 can be used for the study of diseases such as rheumatoid arthritis and septic shock.
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