BTT-3034, a sulfonamide derivative, is an α2β1 integrin inhibitor. BTT-3034 inhibits cell adhesion to rat tail collagen I with an EC 50 of 160 nM and a corresponding E max of 86%. BTT-3034 inhibits collagen binding by an α2 variant carrying the conformationally activating E318W mutation.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Integrin
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