N-Didesmethyladitoprim

Overview

N-Didesmethyladitoprim is a metabolite of Aditoprime ( HY-139743 ). Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC 50 s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Antifolate | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-177337
• CAS No.: 56066-19-4
• Molecular Formula: C13H17N5O2
• Molecular Weight: 275.31
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source