T26A

Overview

T26A is a highly selective prostaglandin transporter ( PGT ) inhibitor.T26A does not interact with the PGT homolog OATPc, blocks PGT -mediated PGE 2 influx, and blocks PGE 2 metabolism.T26A retains PGE 2 in the extracellular compartment and reduces intracellular PGE 2 metabolites.T26A elevates circulating endogenous PGE 2 levels, reduces circulating endogenous PGE 2 metabolite levels, and slows metabolism of exogenously injected PGE 2 in Rattus norvegicus via intravenous injection.T26A does not affect PGE 2 synthesis.T26A can be used for the research of PGT function in adult animals .

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > COX | Products > Signaling Pathways > PGE synthase

Product Information

• Catalog No.: HY-177440
• CAS No.: 958860-12-3
• Molecular Formula: C35H43N11O7
• Molecular Weight: 729.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source