OZD-MET 01

Overview

OZD-MET 01 is a chaperone-med iatedprotein PROTAC-type MET degrader. OZD-MET 01 can inhibit proliferation of H596 and H1437 cells with IC 50 values of 3.07 and 3.5 μM. OZD-MET 01 can be used for the research of cancer , such as non-small cell lung cancer . (Structure Note: Pink: MET ligand ( HY-50878 ); Blue: chaperone ligand ( HY-112078 ); MET ligand-Linker: ( HY-176950 )) (Pink: c-Met/HGFR ligand ( HY-50878 ); Blue: HSP90 ligand ( HY-176951 ); Black: linker ( HY-176952 )).

Application

Products | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > c-Met/HGFR

Product Information

• Catalog No.: HY-177893
• CAS No.: 3048497-38-4
• Molecular Formula: C45H50Cl2FN7O8
• Molecular Weight: 906.83
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source