SA91-0178

Overview

SA91-0178 is a METTL1 inhibitor. SA91-0178 inhibits m 7 G methylation of RNA, reduces SARM1 stability, mitigates NAD + depletion and metabolic reprogramming in macrophages. SA91-0178 demonstrates excellent protective efficacy against multiple organ injury in cecal ligation and puncture (CLP)-induced and ischemia/reperfusion (I/R)-induced mice. SA91-0178 can be used for the study of systemic inflammatory diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > RNA MTase

Product Information

• Catalog No.: HY-178159
• CAS No.: 2244341-81-7
• Molecular Formula: C28H27N3O4
• Molecular Weight: 469.53
• Purity: 98.14%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.32 mM); Clear solution
• Availability: In-stock

Source

Original product source