SARS-CoV-2 PLpro-IN-2

Overview

SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective SARS-CoV-2 papain-like protease ( PLpro ) inhibitor of ( IC 50 =0.06 μM). SARS-CoV-2 PLpro-IN-2 inhibits viral replication and immune evasion. SARS-CoV-2 PLpro-IN-2 exhibits antiviral efficacy in HeLa-ACE2 cells ( EC 50 =2.9 μM). SARS-CoV-2 PLpro-IN-2 is promising for research of COVID-19.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-178160
• CAS No.: 1581755-42-1
• Molecular Formula: C25H27ClN2O
• Molecular Weight: 406.95
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source