JAK1-IN-19

Overview

JAK1-IN-19 (Compound 18) is a potent JAK1 inhibitor with IC 50 s of 0.02, 0.5, 91 and 0.2 nM against JAK1 , JAK2 , JAK3 and TYK2 . JAK1-IN-19 exhibits improved rat and human intrinsic clearance. JAK1-IN-19 can be used for the studies of atopic dermatitis and other autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-178282
• CAS No.: 2169271-17-2
• Molecular Formula: C20H21N7O2
• Molecular Weight: 391.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source