Antifungal agent 137

Overview

Antifungal agent 137 (Compound 4S) is an antifungal agent. Antifungal agent 137 inhibits Phomopsis sp. (PS), with an EC 50 of 0.15 μg/mL. Antifungal agent 137 inhibits lanosterol 14α-demethylase ( CYP51 ), with an IC 50 of 5.00 μg/mL. Antifungal agent 137 disrupts the morphology of PS mycelia, impairs cell membrane integrity, and induces an increase in intracellular ROS levels, triggering oxidative stress. Antifungal agent 137 can be used for the study of fungal infection.

Application

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Product Information

• Catalog No.: HY-178340
• CAS No.: 3032062-22-6
• Molecular Formula: C21H21F4N5O3S
• Molecular Weight: 499.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source