Nav1.7-IN-19

Overview

Nav1.7-IN-19 is a potent, selective and orally active Nav1.7 inhibitor with an IC 50 of 0.49 μM. Nav1.7-IN-19 shows high selectivity for Nav1.7, with selectivities of 312-fold and 662-fold against Nav1.1 and Nav1.5 in the inactivated state. Nav1.7-IN-19 exhibits weak inhibition on hERG potassium channels. Nav1.7-IN-19 exhibits analgesic effect and can be used for the research of neurological disease .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-178494
• CAS No.: 3097995-73-5
• Molecular Formula: C23H23BrClFN4O5S
• Molecular Weight: 601.87
• Purity: 98.87%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (8.31 mM); Clear solution
• Availability: In-stock

Source

Original product source