WML-01 is a fungicide with EC 50 s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum , F. fujikuroi and S. sclerotiorum . WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) ( HY-N6684 ) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic.
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