RIPK1-IN-35

Overview

RIPK1-IN-35 is a selective and orally active RIPK1 inhibitor with an IC 50 of 5.33 nM. RIPK1-IN-35 has a potent protective effect against necroptosis in both human and murine cells. RIPK1-IN-35 shows good therapeutic effects in both TNF-α-induced systemic inflammatory response syndrome and DSS ( HY-116282C )-induced inflammatory bowel disease models. RIPK1-IN-35 can be used to the study of inflammatory diseases related to necroptosis .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > Necroptosis

Product Information

• Catalog No.: HY-178762S
• CAS No.: 3103886-96-7
• Molecular Formula: C26H18D3F3N6O5
• Molecular Weight: 557.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source