7-Oxogedunin

Overview

7-Oxogedunin (Compound 7DG; Compound 16) is a small molecule that protects macrophages from cell pyroptosis induced by anthrax lethal toxin (LT). Its target is protein kinase R ( PKR ). 7-Oxogedunin can widely inhibit the assembly of various inflammasomes ( NLRP1 and NLRP3 ) and the activation of caspase-1 by inhibiting the kinase-independent function of PKR. 7-Oxogedunin has growth inhibitory activity on European corn borer larvae. 7-Oxogedunin can be used for LT toxicity inhibition and pest control research.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Plant Infection | Products > Disease Areas > Insecticide | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Pyroptosis | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Insecticide | Products > Signaling Pathways > Ser/Thr Protease

Product Information

• Catalog No.: HY-178898
• CAS No.: 13072-74-7
• Molecular Formula: C26H30O6
• Molecular Weight: 438.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source