PROTAC GPX4 degrader-5

Overview

PROTAC GPX4 degrader-5 (compound N15) is an efficient and highly selective PROTAC GPX4 degrader ( DC 50 = 28 nM). PROTAC GPX4 degrader-5 can induce ferroptosis and has low toxicity to normal cells. PROTAC GPX4 degrader-5 can significantly increase ROS . PROTAC GPX4 degrader-5 exerts anti proliferative effects on various tumor cells. PROTAC GPX4 degrader-5 is commonly used in cancer research. (Pink: GPX4 ligand ( HY-179294 ); Blue: Others ligand ( HY-N2427 ); Black: linker ( HY-W047688 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis

Product Information

• Catalog No.: HY-178925
• CAS No.: 3119292-91-7
• Molecular Formula: C47H59ClN4O5S
• Molecular Weight: 827.51
• Purity: 95.0%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 2.5 mg/mL (3.02 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source