ONO-7927846

Overview

ONO-7927846 is a potent, orally active, selective and CNS penetrant dual TREK-1/TREK-2 inhibitor (TREK-1 IC 50 = 0.11 μM, TREK-2 IC 50 = 0.29 μM). ONO-7927846 displays robust efficacy in an MK-801 ( HY-15084B ) challenge rat novel object recognition (NOR) paradigm. ONO-7927846 can be used for research on neurological and cognitive disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-179005
• CAS No.: 2640753-27-9
• Molecular Formula: C25H22ClF2N5O2
• Molecular Weight: 497.92
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source