AP-7-168

Overview

AP-7-168, molecular glues , is a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor ( β2AR ). AP-7-168 can promote β2AR homodimerization and inhibit GRK5-mediated β2AR phosphorylation. AP-7-168 can sustain bronchorelaxation in cell and tissue. AP-7-168 can be used for the researches of inflammation and immunology, such as asthma.

Application

Products | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-179226
• CAS No.: 2816062-15-2
• Molecular Formula: C20H19BrF2N4
• Molecular Weight: 433.29
• Purity: 99.89%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source