LT-104A

Overview

LT-104A is a potent PDE4 inhibitor that elevates intracellular cAMP levels ( EC 50 = 1.9 μM) and inhibits PDE4D3 activity ( IC 50 = 9.3 μM). LT-104A activates the cAMP-PKA-CREB anti-inflammatory signaling pathway and suppresses NF-κB-related gene expression ( Il1b and Nos2 ). LT-104A can be used for inflammation-related disease research .

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-179407
• CAS No.: 2574572-03-3
• Molecular Formula: C33H34O7
• Molecular Weight: 542.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source