BKI 1708

Overview

BKI 1708 is a potent and orally active calcium-dependent protein kinase 1 ( CDPK1 ) inhibitor ( IC 50 = 0.7 nM). BKI 1708 exhibits potent activity against Neospora ( IC 50 = 481 nM) and Toxoplasma ( IC 50 = 122 nM). BKI-1708 induces the formation of multinucleated complexes. BKI-1708 efficiently inhibits vertical transmission of both parasites and increases pup survival in mice.

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-179463
• CAS No.: 2332840-70-5
• Molecular Formula: C22H26N4O3
• Molecular Weight: 394.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source