CKBA

Overview

CKBA, a derivative of AKBA ( HY-N0892 ) is an inhibitor of acetyl-CoA carboxylase 1 ( ACC1 ), with an IC 50 of 5.02 μM. CKBA inhibits the differentiation of Th17 cells and has IC 50 values of 3.28 μM for mouse cells and 3.61 μM for human cells. CKBA ointment significantly alleviates psoriasis-like inflammation in mice. CKBA can be used for the study of psoriasis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > Psoriasis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Acetyl-CoA Carboxylase | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-179537
• CAS No.: 1786406-66-3
• Molecular Formula: C37H56O5
• Molecular Weight: 580.84
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution
• Availability: In-stock

Source

Original product source