MS102

Overview

MS102 is an orally active ubiquitin specific peptidase 2 ( USP2 ) inhibitor with an IC 50 of 5.46 μM. MS102 has viable antiviral activity against ACE2 -dependent coronaviruses . MS102 significantly reduces V-domain Ig suppressor of T cell activation ( VISTA ) protein abundance in vitro and in vivo. MS102 can be used for the study of SARS-CoV-2. MS102 can be used in combination with anti-PD-1 immunotherapy to enhance the anti-tumor immune response.

Application

Products | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > VISTA

Product Information

• Catalog No.: HY-179630
• CAS No.: 3058587-77-9
• Molecular Formula: C24H17BrF3N3O3S2
• Molecular Weight: 596.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source