UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α . UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
Products | Products > Disease Areas > Plasmodium Infection | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Guanylate Cyclase | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog
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