RIPK1-IN-38

Overview

RIPK1-IN-38 is an orally active RIPK1 inhibitor with an IC 50 value of 27 nM. RIPK1-IN-38 can inhibit the phosphorylation of RIPK1 and its downstream signaling molecules RIPK3 and MLKL . RIPK1-IN-38 exhibits anti- necroptotic activity. RIPK1-IN-38 has excellent anti-inflammatory efficacy in both the SIRS model and GVHD model. RIPK1-IN-38 can be used for the research of inflammatory and immune-related diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > Necroptosis | Products > Signaling Pathways > Mixed Lineage Kinase | Products > Signaling Pathways > Lactate Dehydrogenase

Product Information

• Catalog No.: HY-179680
• CAS No.: 3092834-30-2
• Molecular Formula: C27H22FN5O2S
• Molecular Weight: 499.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source