Furin-IN-3

Overview

Furin-IN-3 (Compound 9) is a potent and selective proprotein convertase furin inhibitor with a K i of 12.4 nM. Furin-IN-3 shows a K i of 278 nM for PC7. Furin-IN-3 shows a significant antiviral effect on the Furin-dependent H7N7 influenza A virus strain SC35M. Furin-IN-3 can inhibit the cleavage and activation of the viral hemagglutinin (HA), prevent the fusion of the viral membrane with the host cell membrane, and thereby inhibit viral replication and proliferation. Furin-IN-3 can be used for the research of infection , such as influenza virus infection.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > Influenza Virus Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Furin | Products > Signaling Pathways > Influenza Virus

Product Information

• Catalog No.: HY-180145
• CAS No.: 3080672-14-3
• Molecular Formula: C38H47Cl2F9N4O7
• Molecular Weight: 913.69
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source