Lu AF58786

Overview

Lu AF58786 is a potent and selective LRRK2 inhibitor with an IC 50 of 12 nM. Lu AF58786 also exhibits inhibition activity against LRRK2 G2019S and LRRK2 A2016T with IC 50 s of 19 and 93 nM. Lu AF58786 inhibits phosphorylation of LRRK2 , Rab10 and Rab12 in human peripheral blood mononuclear cells. Lu AF58786 can be used for parkinson’s disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > LRRK2

Product Information

• Catalog No.: HY-180320
• CAS No.: 1632368-13-8
• Molecular Formula: C19H16N6
• Molecular Weight: 328.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source