Antimicrobial agent-46 is a inhibitor of Salmonella typhimurium serine acetyltransferase ( StSAT ) with an IC 50 of 48.6 μM. Antimicrobial agent-46 inhibits bacterial growth in minimal medium lacking cysteine (LB 20%). Antimicrobial agent-46 exerts its effect by targeting the cysteine biosynthesis pathway, which is crucial for bacterial persistence and adaptability. Antimicrobial agent-46 exhibits antibacterial activity against the Gram-negative bacterium Escherichia coli . Antimicrobial agent-46 can be used in infection-related research .
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