Etravirine

Overview

Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine.

Application

Products > Drug Discovery > Impurities > Anti-Hiv > Etravirine and Impurities | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B0084-064674
• CAS No.: 269055-15-4
• Molecular Formula: C20H15BrN6O
• Molecular Weight: 435.28
• Purity: >98%
• Storage: Powder : -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
• Solubility: In Vitro : DMSO : 50 mg/mL(114.87 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution

Source

Original product source