UGM-IN-1 (compound 107) is a selective competitive inhibitor of Mycobacterium tuberculosis UDP-Galp mutase (UGM) , encoded by Rv3809c . UGM-IN-1 inhibits the conversion of UDP-galactopyranose ( UDP-Galp ) to UDP-galactofuranose ( UDP-Galf ), thereby blocking the synthesis of key components of the mycobacterial cell wall, including mycolic acid-arabinogalactan ( mAG ) and liparabinomannan ( LAM ), leading to anti-mycobacterial activity against Mycobacterium tuberculosis . UGM-IN-1 is useful for research on tuberculosis, including drug-resistant tuberculosis .
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